Central arterial pressure and patient-specific model parameter estimation based on radial pressure measurements

Abstract

One-dimensional arterial flow simulations are suitable to estimate the aortic pressure from peripheral measurements in a patient-specific arterial network. This study introduces a reduction of the system parameters, and a novel calculation method to estimate the patient-specific set and the aortic curve based on radial applanation tonometry. Peripheral and aortic pressure curves were measured in patients, optimization were carried out. The aortic pressure curves were reproduced well, with an overestimation of the measured Systolic and Mean Blood Pressures on average by 0.6 and 0.5 mmHg respectively, and the Root Mean Square Difference of the curves was 3 mmHg on average.

Keywords:

• 1D arterial network
• patient-specific
• aortic pressure
• method of characteristics

Disclosure statement

All authors of this manuscript have no conflict of interest.

Additional information

Funding

The study was supported by MTA-SE ‘Lendület’ Cardiovascular Imaging Research Group, and was funded by the National Research, Development, and Innovation Fund of Hungary under Grant TKP2021-EGA-02.