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Journal of Asian Natural Products Research Volume 14, 2012 - Issue 6
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Original Articles

Metabolites from endophytic fungus A12 of Dracaena cambodiana

Dong-Dong Chang Hainan Key Laboratory for Research and Development of Natural Products from Li Folk Medicine, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, 571101, China; Haikou Key Laboratory for Research and Development of Tropical Natural Products, Haikou, 571101, China
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Wen-Jian Zuo Hainan Key Laboratory for Research and Development of Natural Products from Li Folk Medicine, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, 571101, China; Haikou Key Laboratory for Research and Development of Tropical Natural Products, Haikou, 571101, China
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Wen-Li Mei Hainan Key Laboratory for Research and Development of Natural Products from Li Folk Medicine, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, 571101, China; Haikou Key Laboratory for Research and Development of Tropical Natural Products, Haikou, 571101, ChinaCorrespondence[email protected]
&
Hao-Fu Dai Hainan Key Laboratory for Research and Development of Natural Products from Li Folk Medicine, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, 571101, China; Haikou Key Laboratory for Research and Development of Tropical Natural Products, Haikou, 571101, ChinaCorrespondence[email protected]
Pages 577-580 | Received 15 Dec 2011, Accepted 27 Mar 2012, Published online: 09 May 2012
 
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Abstract

A new drimane sesquiterpene, 1α,7α-dihydroxyconfertifolin (1), along with two known compounds 2 and 3, was isolated from endophytic fungus A12 of Dracaena cambodiana. The new compound was elucidated by HR-ESI-MS and spectroscopic techniques (IR, UV, 1D, and 2D NMR). Compound 2 showed inhibitory bacterial activity against Staphylococcus aureus with diameter of the inhibition zone of 13.5 mm.

Acknowledgments

This research was financially supported by National Natural Science Foundation of China (No. 31070321), Natural Science Foundation of Hainan (310083), and National Nonprofit Institute Research Grant of CATAS-ITBB (1041, 0219).

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