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Articles

Synthesis of three OSW-1 analogs with maltose side chains bearing different protection groups

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Pages 43-52 | Received 03 Sep 2013, Accepted 04 Nov 2013, Published online: 06 Dec 2013
 

Abstract

In order to simplify the synthesis of OSW-1's disaccharide side chain and explore the structure–activity relationship of OSW-1, three 16α-O-maltose OSW-1 analogs carrying three maltose side chains bearing different protections were designed and synthesized.

Acknowledgments

Financial support of this research by the National Natural Science Foundation of China (NNSFC 30772632) and the National Program of New Drug Innovation and Production (2009ZX09301-003-9-1) is gratefully acknowledged by the authors.

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