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Journal of Asian Natural Products Research Volume 17, 2015 - Issue 2
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Natural products as antidepressants documented in Chinese patents from 1992 to 2013

Chang-Li SunState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming650201, China;University of Chinese Academy of Sciences, Beijing100039, China
,
Chang-An GengState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming650201, China
,
Xiu-Juan YinState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming650201, China;University of Chinese Academy of Sciences, Beijing100039, China
,
Xiao-Yan HuangState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming650201, China
&
Ji-Jun ChenState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming650201, ChinaCorrespondence[email protected]
Pages 188-198 | Received 04 Aug 2014, Accepted 05 Nov 2014, Published online: 06 Dec 2014
 
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Abstract

Depressive disorder is a severe psychiatric problem all over the world. Clinical therapeutic agents for the treatment of depression in the market targeting on monoamine neurotransmitters are far from satisfaction due to their adverse effects. Novel classes of antidepressant agents with different mechanisms and low toxicity are needed. Natural products from traditional Chinese medicines have been revealed as new sources to cure the depressive symptoms with various chemical structures and promising activities. This paper reviews natural products as antidepressants documented in Chinese patents so far.

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