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Journal of Asian Natural Products Research Volume 17, 2015 - Issue 5: Celebration to Professor Xinsheng Yao's 80th birthday
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Articles

Five new bioactive compounds from Chenopodium ambrosioides

Kun SongState Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing100050, ChinaView further author information
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Jian ZhangDepartment of Cell and Molecular Biology, Research Institute of Orthopedics & Traumatology, Foshan Hospital of TCM, Foshan528000, ChinaView further author information
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Peng ZhangState Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing100050, China;Department of Traditional Chinese Medicinal Chemistry, Beijing University of Chinese Medicine, Beijing100102, ChinaView further author information
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Hong-Qing WangState Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing100050, ChinaView further author information
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Chao LiuState Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing100050, ChinaView further author information
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Bao-Ming LiState Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing100050, ChinaView further author information
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Jie KangState Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing100050, ChinaCorrespondence[email protected] [email protected]
View further author information
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Ruo-Yun ChenState Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing100050, ChinaView further author information
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Pages 482-490 | Received 01 Apr 2015, Accepted 15 Apr 2015, Published online: 22 May 2015
 
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Abstract

Five new bioactive compounds, chenopodiumamines A–D (1–4) and chenopodiumoside A (5), were isolated from the ethanol extract of Chenopodium ambrosioides. The structures of these compounds were elucidated by various spectroscopic means (UV, IR, HR-ESI-MS, 1D and 2D NMR). Compounds 1–3 had moderate antioxidant and anti-inflammatory activities.

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

This work was financially supported by grants from National Science and Technology Major Projects for “Major New Drugs innovation and Development” [grant number 2012ZX09103201-043].

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