New sesquiterpenoid glycoside and phenylpropanoid glycosides from the tuber of Ophiopogon japonicus

Abstract

A new sesquiterpenoid glycoside, cryptomeridiol 11-O-β-d-xylopyranosyl-(1→6)-β-d- glucopyranoside (1), two new phenylpropanoid glycosides, 3,4-dihydroxy-allylbenzene 3-O-β-d-glucopyranosyl-4-O-β-d-apiofuranosyl-(1→6)-β-d-glucopyranoside (2), and 3,4,5-trihydroxy-allylbenzene 3-O-β-d-glucopyranosyl-4-O-β-d-glucopyranoside (3), along with four known phenylpropanoid glycosides (4–7), were isolated from the tuber of Ophiopogon japonicus. Compounds 4–7 were obtained from the genus Ophiopogon for the first time. Their structures were elucidated by spectroscopic methods, including 1D and 2D NMR and HR-ESI-MS.

Keywords:

• Ophiopogon japonicus
• sesquiterpenoid glycoside
• phenylpropanoid glycoside

Acknowledgments

The authors gratefully acknowledge the technical supports and other helps of Dr. Ren-Yi Yan, Yu-Ming Wang, Xin-Guang Sun, and Xu Pang. The NMR spectra were tested at the National Center of Biomedical Analysis, and thanks to the staffs.

Disclosure statement

No potential conflict of interest was reported by the authors.