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Original Articles

A new medermycin analog from the marine-derived actinomycetes Streptomyces sp. ZS-A45

, , , , &
Pages 826-831 | Received 10 Dec 2017, Accepted 16 May 2018, Published online: 27 Jun 2018
 

Abstract

A new medermycin analog (1) was isolated from the marine-derived actinomycetes Streptomyces sp. ZS-A45. The structure elucidation of compound 1 was determined by the HRESIMS and extensive NMR analysis. And compound 1 exhibited significant cytotoxicity against PC3 cell lines with IC50 values of 0.81 ± 0.42 μm.

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