Abstract
Two new benzoic acid derivatives (1–2), together with four known compounds (3–6) have been isolated from the n-BuOH soluble fraction of ethanolic extract from Ailanthus altissima. The gross structures of the new compounds were deduced by detailed spectroscopic analysis including HRESIMS and 1D/2D NMR spectroscopy. The stereochemistry of 1 was determined by modified Mosher’s method. All compounds were evaluated for their neuroprotective effects against H2O2-induced oxidative stress in human neuroblastoma SH-SY5Y cells and none of them displayed obvious neuroprotective activities.
Graphical Abstract
![](/cms/asset/c762f875-9fb4-4fcc-a1a5-b9f4fe31b6a7/ganp_a_1715952_uf0001_c.jpg)
Disclosure statement
No potential conflicts of interest were reported by the authors.