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Research Articles

Two novel sesquiterpenes and one new monoterpene from the aerial part of Artemisia tournefortiana

, &
Pages 334-341 | Received 23 Nov 2021, Accepted 25 Jun 2023, Published online: 14 Jul 2023
 

Abstract

Two novel sesquiterpenes and one new monoterpene, together with eight reported compounds were isolated from dichloromethane–soluble extract of the aerial part of Artemisia tournefortiana Reichb. Their relative and absolute structures were elucidated based on the analysis of 1D and 2D NMR spectra, HRESIMS, and calculated electronic circular dichroism (ECD). Two sesquiterpenes (1 and 2) showed no inhibition effect in anti-inflammatory and cytotoxic activity tests. Three new terpenes (13) were tested for antibacterial activity, compounds 2 and 3 showed moderate antibacterial activities with minimum inhibitory concentrations (MICs) between 264 and 556 μg/ml.

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

This work was financially supported by the National Natural Science Foundation of China [No. U1703235], Xinjiang International Science & Technology Cooperation Program [No. 2019E01017], Central Asia Drug Discovery and Development Centre of Chinese Academy of Science [No. CAM201904], and Youth Innovation Promotion Association of the Chinese Academy of Sciences [No. 2020432].

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