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Journal of Asian Natural Products Research Volume 8, 2006 - Issue 5
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Original Articles

A new spiro-sesquiterpene from the sponge Dysidea fragilis

Note

Z.-G. Yu School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, 110016, China
,
K.-S. Bi School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, 110016, China
,
Y.-W. Guo Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, State Key Laboratory of Drug Research, Zhangjiang Hi-Tech Park, Zu Chong Zhi Road 555, Shanghai, 201203, ChinaCorrespondence[email protected]
,
E. Mollo Istituto di Chimica Biomolecolare del CNR, Puzzuoli (Na), 80078, Italy
&
G. Cimino Istituto di Chimica Biomolecolare del CNR, Puzzuoli (Na), 80078, Italy
Pages 467-470 | Received 20 Sep 2004, Accepted 25 Dec 2004, Published online: 04 Sep 2006
 
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Abstract

A new spiro-sesquiterpene, spirofragilin (1), along with a known related sesquiterpene, dehydroherbadysidolide (2), have been isolated from the marine sponge Dysidea fragilis collected in the South China Sea. The structure of 1 was elucidated on the basis of detailed spectroscopic analysis.

Acknowledgements

This research was financially supported by “National Marine 863 Project (2001AA620 40 3 and 2003AA624030)”, “National Natural Science Foundation for Outstanding Chinese Youths” (No.30125044) and partially funded by CNR(Italy)/CAS(China) Joint Projects 2001/2004.

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