Abstract
Six thiophenes were isolated and purified from ethanol extract of the roots of Echinops latifolius Tausch. Their structures were identified on the basis of spectral data. Among them, 5-(3-hydroxmethyl-3-isovaleroyloxyprop-1-ynyl)-2,2′-bithiophene (6) is a new compound, and 5-(3-hydroxy-4-isovaleroyloxybut-1-ynyl)-2,2′-bithiophene (5) was isolated from this plant for the first time.
Acknowledgements
We are grateful to the Analytical Detective Center, Shenyang Pharmaceutical University, for recording MS and NMR spectra.