Heteroclitin H, a new lignan from Kadsura heteroclita

Abstract

A new dibenzocyclooctadiene lignan, heteroclitin H (1), was isolated together with seven known compounds, heteroclitin D (2), interiorin B (3), interiorin (4), neokasuranin (5), interiotherin C (6), gomisin J (7) and (+)-anwulignan (8), from the stems of Kadsura heteroclita. Their structures were elucidated by spectroscopic methods. This is the first report of the isolation of compounds 3, 5, 6, 7 and 8 from K. heteroclita.

Keywords:

• Dibenzocyclooctadiene lignan
• Kadsura heteroclita
• Schisandraceae
• Kadsura
• Heteroclitin H

Acknowledgements

This investigation was supported by grants from the National Natural Science Foundation of China (30271586), the Foundation for Doctoral Programs (2000026519), the Trans-Century Training Program Foundation for the Talents, and the Teaching and Research Award Program for Outstanding Young Teachers in Higher Education Institutions (1999–71) from the Ministry of Education, People's Republic of China.