Stilbene C-glucosides from Cissus repens

Abstract

Four new stilbene C-glucosides, namely trans-3-O-methyl-resveratrol-2-C-β-glucoside (1), cis-3-O-methyl-resveratrol-2-C-β-glucoside (2), trans-3-O-methyl-resveratrol-2-(2-p-coumaric)-C-β-glucoside (cissuside A) (3), and trans-3-O-methyl-resveratrol-2-(3-p-coumaric)-C-β-glucoside (cissuside B) (4), were isolated from the aerial parts of Cissus repens, along with known trans-resveratrol (5), trans-resveratrol-2-C-β-glucoside (6) and cis-resveratrol-2-C-β-glucoside (7). Their structures were established by spectroscopic methods. Stilbene C-glucosides were found in the genus Cissus for the first time.

Keywords:

• Cissus repens
• Vitaceae
• Stilbenes
• C-Glucosides
• Resveratrol
• Cissuside

Acknowledgements

This work was financially supported by two grants from National Natural Science Foundation of China (No. 30370957) and Natural Science Foundation of Yunnan Province, China (No. 2003C0061M). We also thank Xishuangbanna Tropical Botanical Garden, Chinese Academy of Sciences, for its help in collecting the plant material.