Two new bioactive prenylated dihydroflavanoids from the medicinal plant Dolichos tenuicaulis (Baker) Craib

Abstract

Two new prenylated dihydroflavanoids have been isolated from the medicinal plant of Dolichos tenuicaulis (Baker) Craib. Their structures were elucidated as (2S)-5,2′,6′-trihydroxy-8-prenyl-6,7-(3-prenyl-2,2-dimethylpyrano)-3′,4′-(2,2-dimethyl-1-keone-cyclohexadiene)-flavanone (1) and (2S)-5,2′,6′-trihydroxy-8-prenyl-6,7-(3-prenyl-2,2-dimethyl-1-keone-cyclohexadiene)-flavanone (2) on the basis of spectroscopic analysis.

Keywords:

• Dolichos tenuicaulis (Baker) Craib
• Prenylated flavanoid
• Dihydroflava-noid
• Anti-cancer activity

Acknowledgements

The excellent technical assistance for chemical structure elucidation from Dr Chunhui Ma (Shanghai Institute of Materia Medica, Chinese Academy of Science, Shanghai, China) is gratefully acknowledged.