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Original Articles

Poriacosones A and B: two new lanostane triterpenoids from Poria cocos

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Pages 640-646 | Received 17 Jan 2007, Accepted 23 May 2007, Published online: 17 Jul 2008
 

Abstract

Two new lanostane triterpenoids, poriacosones A (8) and B (9), together with eight known compounds were isolated from the sclerotia of Poria cocos (Schw.) Wolf (Polyporaceae), and identified by spectroscopic analysis, including IR, UV, CD, ESI-TOF-MS, HR-SIMS, 1D-, and 2D-NMR spectra. The structures of the new compounds were established as 3α,16α-dihydroxy-24-oxolanost-7,9(11)-dien-21-oic acid (8) and 3β,16α-dihydroxy-24-oxolanost-7,9(11)-dien-21-oic acid (9).

Acknowledgements

This research was supported by the National Natural Science Foundation of China (20572007), the National High Technology Research and Development Program of China (2002AA2Z343C), and the Beijing Municipal Special-purpose Science Foundation of China (Z0004105040311).

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