Two new steroidal saponins from the rhizome of Polygonatum sibiricum

Abstract

Two new furostanol saponins, polygonoides A (1) and B (2), along with three known compounds, were obtained from the ethanolic extract of the rhizome of Polygonatum sibiricum Redoute. On the basis of acid hydrolysis and comprehensive spectroscopic analyses, the structures of polygonoides A and B were elucidated as (25R)-26-O-β-d-glucopyranosyl-furost-5,22(23)-dien-3β,26-diol-3-O-α-l-rhamnopyranosyl-(1 → 3)-β-d-glucopyranosyl-(1 → 4)-[α-l-rhamnopyranosyl-(1 → 2)]-β-d-glucopyranoside (1) and 22α-(propionyloxy)-furost-5-en-3β,20α-diol-3-O-β-d-glucopyranosyl-(1 → 4)-[α-l-rhamnopyranosyl-(1 → 2)]-β-d-glucopyranoside (2).

Keywords:

• Polygonatum sibiricum
• furostanol saponins
• polygonoide A
• polygonoide B

Acknowledgements

This work was supported by the Science and Technology Bureau of Zhuhai City, Guangdong Province, China.