Two new glycosides from Breynia vitis-idaea

Abstract

A new sulfur-containing spiroketal glycoside, breynin I (1), and a new terpenic glycoside, breyniaionoside E (2), together with 10 known compounds, were isolated from the aerial parts of Breynia vitis-idaea (Euphorbiaceae), a traditional Chinese medicine used for the treatment of chronic bronchitis and wounds. Their structures were elucidated on the basis of spectroscopic analysis and modified Mosher's method.

Keywords:

• Breynia vitis-idaea
• Euphorbiaceae
• sulfur-containing sesquiterpene glycoside
• terpenic glycoside

Acknowledgements

This work was financially supported by the National Science and Technology Major Project ‘Key New Drug Creation and Manufacturing Program’, China (No. 2009ZX09301-001) and Key Project of Chinese Academy of Sciences (No. KSCX2-YW-R-184). The authors wish to thank Professors Ying Zhou and Ding Fang of Guangxi Institute of Traditional Chinese Medicine for providing and identification of the plant material.