Aptasensor Based on Microfluidic for Foodborne Pathogenic Bacteria and Virus Detection: A Review

Abstract

In today’s world, which is entangled with numerous foodborne pathogenic bacteria and viruses, it appears to be essential to rethink detection methods of these due to the importance of food safety in our lives. The vast majority of detection methods for foodborne pathogenic bacteria and viruses have suffered from sensitivity and selectivity due to the small size of these pathogens. Besides, these types of sensing approaches can improve on-site detection platforms in the fields of food safety. In recent, microfluidics systems as new emerging types of portable sensing approaches can introduce efficient and simple biodevice by integration with several analytical methods such as electrochemical, optical and colorimetric techniques. Additionally, taking advantage of aptamer as a selective bioreceptor in the sensing of microfluidics system has provided selective, sensitive, portable and affordable sensing approaches. Furthermore, some papers use increased data transferability ability and computational power of these sensing platforms by exploiting smartphones. In this review, we attempted to provide an overview of the current state of the recent aptasensor based on microfluidic for screening of foodborne pathogenic bacteria and viruses. Working strategies, benefits and disadvantages of these sensing approaches are briefly discussed.

Keywords:

• Colorimetric aptasensor
• electrochemical aptasensor
• food safety
• foodborne pathogenic bacteria
• microfluidics
• optical aptasensor
• point of care
• virus

Acknowledgments

The authors express their gratitude to the Deanship of College of Applied Sciences, University of Anbar for supporting this work.