Figures & data
Figure 1. Models used to study GAS transcriptome. Advantages (PROS) and disadvantages (CONS) of current models (plain lines) used for GAS transcriptomic studies as well as the clinical manifestations there are reproducing (MIMICRY). Dash lines highlight that the more clinically relevant model for GAS transcriptomic studies is the challenge human infection model (CHIM). OP: oro-pharyngeal, NF: necrotizing fasciitis.
Table 1. Expression of virulence genes in different conditions is highlighted by blue (down), red (up) or green boxes (both) compared to a control condition and at least in one serotype.
Figure 2. GAS encounters different environments during its host colonization and/or invasion.
Supplemental material