Reactions of Hydrazonoyl Halides 47¹: Synthesis of Some New 2,3-dihydro-1,3,4-thiadiazoles, Triazolo[4, 3-a]pyrimidines, and Pyrazolo[3, 4-d]pyridazines with Expected Biological Activity

2,3-dihydro-1,3,4-thiadiazoles, triazolino[4, 3-a]pyrimidines, andpyrazolo[3, 4-d]pyridazines were synthesized in good yields from reactions of hydrazonoyl halides with alkyl carbodithioates, pyrimidine-2-thione, and substituted prop-2-ene-1-one, respectively. All structures of the newly synthesized compounds were elucidated by elemental analysis, spectral data, and an alternative synthesis method. Some of the new compounds were tested towards bacteria and fungi.

Keywords:

• 2,3-Dihydro-1,3,4-thiadiazolines
• cycloaddition
• pyrazolo[3,4-d]pyridazines
• triazolino[4,3-a]pyrimidines