The Preparation of Acylselenourea and Selenocarbamate Using Isoselenocyanate

Abstract

Acyl isoselenocyanates were prepared by a reaction of acyl chloride with KSeCN. The acyl isoselenocyanates formed in situ were ready for further reaction without concentration. N-Acyl selenoureas were obtained by a reaction of acyl isoselenocyanates with amines. The reaction of acyl isoselenocyanates with nucleophiles gave the corresponding selenocarbamate. All the compounds were well characterized by using spectral data, such as ¹³C and ⁷⁷Se NMR and X-ray diffraction.

Keywords:

• Isoselenocyanate
• selenourea
• selenocarbamate

Acknowledgments

This work was supported by a Grant in Aid for Science Research from the Ministry of Education, Culture, Sports, Science and Technology of Japan (No. 17550099) to which we are grateful.

Notes

^aA product was generated in a reaction mixture in situ quantitatively. However, it decomposed in the process of purification.