Synthesis and Biocidal Activity of Organophosphates Derived from Benzothiazole

Abstract

The synthesis, biocidal activity, and spectroscopic data of a new series of S-phosphorylated/thiophosphorylated derivatives of 2-(2′-mercaptophenyl) benzothiazole are reported in this study. Derivatives were prepared by reacting 2-(2′-mercaptophenyl) benzothiazole with phosphorus oxychloride/phosphorus thiochloride in different molar ratios [1:1, 2:1, 3:1]. All of the derivatives were found to be antifungal agents with less toxicity than the standard Dithane M-45.

Keywords:

• Fungicidal activity
• S-phosphorylated/thiophosphorylated derivatives of 2-(2′-mercaptophenyl) benzothiazole

We are thankful to the Head of the Department of Chemistry, University of Rajasthan, Jaipur, India, for providing necessary facilities. Priyanka Jhajharia is grateful to University Grants Commission, New Delhi, India, for the financial support in the form of Junior Research Fellow wide grant No. 10-2(5)/2006(i)-E.U. II.