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Original Articles

Synthesis of Quinoline-Based Thieno-Seleno-Phenylquinazolinones

, , , , &
Pages 460-470 | Received 04 Apr 2008, Accepted 02 May 2008, Published online: 04 Feb 2009
 

Abstract

The synthesis of quinoline-substituted phenylquinazolinones containing sulfur and selenium is described. These molecules were isolated from a series of reactions of 2-phenyl-4H-3,1-benzoxazin-4-one with 2-chloro, 2-thieno, and 2-selenoquinoline-3-carbaldehyde hydrazones. The structure of the isolated compounds has been elucidated on the basis of IR, 1 H NMR, mass spectral, and elemental analysis data.

One of the authors (H.R. Prakash Naik) thanks the Indian Institute of Science for providing facilities for spectral analyses and SC/ST cell, Kuvempu University for awarding the Junior Research Fellowship (JRF).

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