Abstract
Treatment of 5-bromo-2-acetyl benzofuran with hydrazine followed by condensation of the resulting hydrazone with different quinoline derivatives gave the corresponding Schiff bases. Reaction of these Schiff bases with thioacetic acid furnished the target thiazolidinone molecule. Some of the newly synthesized compounds show promising analgesic and antimicrobial activity.
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Acknowledgments
The authors thank the Indian Institute of Science Bangalore and Karnataka University Dharwad for providing spectral data. One of the authors (V.K.B.) thanks Kuvempu University for awarding a research fellowship.