N,N′-Dibromo-N,N′–1,2-ethanediylbis(benzene sulfonamide) as an Efficient Catalyst for Acetylation and Formylation of Alcohols Under Mild Conditions

Abstract

An efficient method for the acylation and formylation of alcohols and phenols by using an acylating/formylating agent (acetic anhydride and formic acid) in the presence of a catalytic amount of N,N′-dibromo-N,N′–1,2-ethanediylbis(benzene sulfonamide) under mild and solvent-free conditions at room temperature in good to excellent yields is described. The use of protic acids and metal Lewis acids is avoided.

Keywords:

• Acetic anhydrides
• acetylation
• alcohols
• N,N′-dibromo-N,N′-1,2-ethanediylbis(benzene sulfonamide)
• formic acid
• formylation
• phenols

Acknowledgments

The authors acknowledge the Bu-Ali Sina University and Kurdistan University Research Councils for partial support of this work.

Notes

^a All products were characterized by comparison of their spectral data (¹H NMR, IR) with those of authentic samples. ^{23 , 24 , 25 , 26}

^b Isolated yields.

^c References for previously reported products.

^a All products were characterized by comparison of their spectral data (¹H NMR, IR) with those of authentic Samples. ^{23 , 24 , 25 , 26}

^b Isolated yields.

^c References for previously reported products.