GRAPHICAL ABSTRACT
![](/cms/asset/f4d0fdf7-47df-4681-9df4-20b36d12d7aa/gpss_a_979992_uf0001_oc.jpg)
Abstract
A new stereoselective synthesis of P-chirogenic secondary phosphine oxides was described, by hydrolysis of aminophosphine borane prepared from ephedrine, then decomplexation. These compounds were used for the preparation of P-chirogenic diphosphine dioxides and biarylphosphine oxides, thanks to the aryne chemistry.