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Phosphorus, Sulfur, and Silicon and the Related Elements Volume 190, 2015 - Issue 9
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Original Articles

Nano-BF3.SiO2 Catalyst-Promoted Michaelis-Arbuzov Reaction: Solvent-Free Synthesis and Antimicrobial Evaluation

Mavallur VaralakshmiDepartment of Chemistry, Sri Venkateswara University, Tirupati, 517502, Andhra Pradesh, India
,
Doddaga SrinivasuluDepartment of Chemistry, Sri Venkateswara University, Tirupati, 517502, Andhra Pradesh, IndiaCorrespondence[email protected]
&
Venkata S. KotakadiDST-PURSE Centre, Sri Venkateswara University, Tirupati, 517502, Andhra Pradesh, India
Pages 1518-1524 | Received 14 Sep 2014, Accepted 03 Dec 2014, Published online: 17 Aug 2015
 
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GRAPHICAL ABSTRACT

Abstract

A simple, convenient synthetic route for the synthesis of novel dialkyl heteroaryl phosphonates by a reusable and green nano-BF3.SiO2 solid catalyst under solvent-free conditions through Michaelis–Arbuzov reaction with high yields is presented. All the newly synthesized compounds were characterized by spectral data and screened for their antimicrobial activity. Some of the compounds exhibited potent antibacterial activity against all the tested pathogens, and warrant further investigation.

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