An Efficient One-Pot Synthesis of (1,2-Dihydro-2-Oxoquinoxaline-3-Yl)Methyl Carbamodithioate Derivatives From Benzene-1,2-Diamines, Ethyl Bromopyruvate, CS₂, and Secondary Amines

GRAPHICAL ABSTRACT

Abstract

A mild, convenient, and practical one-pot procedure for the direct synthesis of (1,2-dihydro-2-oxoquinoxaline-3-yl)methyl carbamodithioate derivatives is described via four-component reaction of benzene-1,2-diamines, ethyl bromopyruvate, CS₂, and secondary amines in MeCN at room temperature.

Keywords:

• Ethyl bromopyruvate
• (1,2-dihydro-2-oxoquinoxaline-3-yl)methyl carbamodith-ioate
• benzene-1,2-diamines
• one-pot reaction
• secondary amine