Nano Fe₃O₄@ZrO₂/SO₄²⁻: A highly efficient catalyst for the protection and deprotection of hydroxyl groups using HMDS under solvent-free condition

GRAPHICAL ABSTRACT

ABSTRACT

In this work, we introduce a new procedure for the protection and deprotection process of various types of alcohols and phenols by HMDS in the presence of nano magnetic sulfated zirconia (Fe₃O₄@ZrO₂/SO₄²⁻) as a solid acid catalyst under very mild and solvent-free condition. This method has interesting advantages like short reaction times and a simple workup process. With regard to some outstanding benefits of this new heterogeneous catalyst such as excellent yield, reusability of the catalyst and easy thermal stability, high acidity, strong and excellent magnetic properties, this method can be very interesting in aspect of green chemistry Principles.

KEYWORDS:

• Magnetic nanocatalyst
• Fe₃O₄@ZrO₂/SO₄²⁻
• trimethylsilyl ethers
• HMDS
• solvent-free condition

Funding

The authors gratefully acknowledge the partial support from the research council of the Iran University of Science and Technology (IUST).