GRAPHICAL ABSTRACT
ABSTRACT
A novel and efficient dicyclohexylcarbodiimide-promoted protocol for the selective and controllable esterification of P(O)OH compounds using O-nucleophiles (alcohols and phenols) as efficient esterification reagents is described. This method features a high efficiency and good functional-group tolerance, meaning a simple way to synthesize a broad spectrum of phosphinic and phosphoric acid esters from basic starting materials with moderate to excellent yields.
Acknowledgment
This work was supported by National Natural Science Foundation of China (21606080, 21676077, 21476068), Scientific Research Fund of Hunan Provincial Education Department (16B111).