A recent approach for the synthesis of 1,2,4-triazine systems bearing and/or containing phosphorus atoms as donor-acceptor interaction and their biocidal affects: An overview

Abstract

This review reports the developed methods for the synthesis of polyfunctional 1,2,4-triazine systems bearing and/or containing phosphorus atoms as donor-acceptors interactions. Most of the synthetic methods depend on the interaction between an amino group of the side chain of 1,2,4-triazine with phosphorus reagents. The biological activities, i.e. their biocidal affects as antioxidants, antimicrobials, anti-inflammatory as well as molluscicidal agents against some snails are discussed.

Graphical Abstract

Keywords:

• Phosphorus
• molluscicidal
• 1,2,4-triazines
• polyfunctional
• phosphorylation

Acknowledgements

The author would like to express unlimited thank you for Prof. Dr. Reda M. Abdel-Rahman (D.SC. Heterocyclic Chemistry) for the main role in this overview. This work is dedicated to the memory of Professor Mohammad Saleh Tawfik Makki Professor of Organic Chemistry, King Abdulaziz University who sadly passed away on October 30, 2019.

Conflict of interest

The authors confirm that this article content has no conflict of interest.