Abstract
Target phosphorylated betaines (1–3) were obtained by the quaternization reaction between potassium salt of amino phosphonate and alkyl halides. The structures of the compounds were investigated by IR and NMR spectroscopy. The molecular structure of isopropyl [(N-octyl-N,N-diethylammonio)methyl]phosphonate (2) was determined by a single crystal X-ray analysis. Compound 2 demonstrates a high antibacterial activity against bacterial strain Staphylococcus epidermidis.
Graphical Abstract
![](/cms/asset/8956ceac-cf9e-4a4d-a903-41ca1964b658/gpss_a_2021527_uf0001_c.jpg)
Disclosure statement
No potential conflict of interest was reported by the author(s).