Abstract
Phosphoenolpyruvate is widely involved in a variety of biochemical processes. Herein we report a facile synthetic method for phosphoenolpyruvates and their C-P and N-P analogues via the classic Perkow reaction under mild solvent-free conditions. A moderate to excellent E/Z-stereoselectivity was observed giving the E-isomer as the main product, as determined by full NMR spectroscopy analysis.
Graphical Abstract
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Disclosure Statement
There are no conflicts to declare.