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Articles

Real-world healthcare resource utilization and costs associated with tisagenlecleucel and axicabtagene ciloleucel among patients with diffuse large B-cell lymphoma: an analysis of hospital data in the United States

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Pages 2052-2062 | Received 07 Jan 2022, Accepted 22 Mar 2022, Published online: 14 Apr 2022

Figures & data

Figure 1. Sample selection flowchart. axi-cel: axicabtagene ciloleucel; CAR-T: chimeric antigen receptor modified T-cells; DLBCL: diffuse large B-cell lymphoma; Q: quarter; tisa-cel: tisagenlecleucel.

Figure 1. Sample selection flowchart. axi-cel: axicabtagene ciloleucel; CAR-T: chimeric antigen receptor modified T-cells; DLBCL: diffuse large B-cell lymphoma; Q: quarter; tisa-cel: tisagenlecleucel.

Table 1. Patient baseline characteristics.

Table 2. Infusion center characteristics.

Table 3. HRU associated with tisa-cel and axi-cel.

Figure 2. Healthcare costs in the tisa-cel and axi-cel cohorts. During both the infusion encounter and over the entire follow-up period, tisa-cel was associated with significantly lower overall costs and inpatient costs compared with axi-cel (all comparisons p< .05). axi-cel: axicabtagene ciloleucel; IP: inpatient; OP: outpatient; PPPM: per-patient-per-month; tisa-cel: tisagenlecleucel.

Figure 2. Healthcare costs in the tisa-cel and axi-cel cohorts. During both the infusion encounter and over the entire follow-up period, tisa-cel was associated with significantly lower overall costs and inpatient costs compared with axi-cel (all comparisons p< .05). axi-cel: axicabtagene ciloleucel; IP: inpatient; OP: outpatient; PPPM: per-patient-per-month; tisa-cel: tisagenlecleucel.

Table 4. AEs and related treatments in the tisa-cel and axi-cel cohorts.

Supplemental material

GLAL-2022-0026-File004.docx

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Data availability statement

The data were provided to the authors under an agreement with Premier Healthcare Solution, Inc. Researchers can request access from Premier directly and pay the applicable fee (https://products.premierinc.com/applied-sciences/solutions).