Weighted single step GWAS reveals genomic regions associated with economic traits in Murrah buffaloes

Figures & data

Figure 1. Diagrammatic representation of analysis pathway.

Table 1. Descriptive statistics and genetic parameter estimates for economically important traits in Murrah buffaloes.

Traits	Mean ± SD	N	h^2±SE	Additive Var	Residual Var
6M (kg)	110.45 ± 24.33	1725	0.31 ± 0.05	145.49	322.88
12M (kg)	194.51 ± 48.26	1995	0.20 ± 0.04	416.81	1648.2
18M (kg)	268.86 ± 56.81	1951	0.30 ± 0.04	820.66	1839.4
24M (kg)	342.84 ± 64.15	2041	0.26 ± 0.04	817.9	2230.7
305D MY (kg)	1850 ± 589.62	1940	0.21 ± 0.05	66790	242530
LL (days)	315.87 ± 82.47	1943	0.08 ± 0.04	556.12	6074.7
TMY (kg)	1993.7 ± 723.6	1943	0.19 ± 0.04	92648	382950
DP (days)	173.10 ± 91.65	1327	0.22 ± 0.06	1750.8	5952.7
AFC (days)	1337.1 ± 194.4	1920	0.11 ± 0.04	4006.2	32228
CI (days)	496.37 ± 132.4	1452	0.04 ± 0.05	720.52	15553
FSP (days)	189.48 ± 131.9	1457	0.09 ± 0.05	1476.1	14558

Additive variance present in the population.

Table 2. Details of genomic regions and chromosomes associated with different traits.

Trait	No. of genomic regions	Chromosome identified with important SNP windows
Growth traits
For 6M body weight	31	BBU 9, 5, 7, 24 and 23
12M body weight	19	BBU 1
18M body weight	19	BBU 2, 4, 6 and 25
24M body weight	36	BBU 11
Production traits
305 day milk yield	17	BBU 9, 8, 20, 21, and 16
Lactation length	10	BBU 3 and 4
Dry period	8	BBU 18, 5, 20 and 6
Reproduction traits
Age at First Calving	16	BBU 14 and 3
Calving Interval	8	BBU17
First Service Period	18	BBU 13 and 9