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Integrated Ferroelectrics
An International Journal
Volume 182, 2017 - Issue 1: Proceedings of the Fifteenth China International Nanoscience and Technology Symposium (CINSTS16), Part V
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Original Articles

Core/shell structured hollow mesoporous sSiO2@mSiO2 nanocapsules for anticancer drug delivery

Liang HeInstitute of Biomedical Materials and Engineering, College of Chemistry and Chemical Engineering, Qingdao University, Qingdao, China
,
Yi-Fan WangInstitute of Biomedical Materials and Engineering, College of Chemistry and Chemical Engineering, Qingdao University, Qingdao, China;Laboratory for New Fiber Materials and Modern Textile, Growing Base for State Key Laboratory, College of Materials Science and Engineering, Qingdao University, Qingdao, China
,
Bing YuInstitute of Biomedical Materials and Engineering, College of Chemistry and Chemical Engineering, Qingdao University, Qingdao, China;Laboratory for New Fiber Materials and Modern Textile, Growing Base for State Key Laboratory, College of Materials Science and Engineering, Qingdao University, Qingdao, China
,
Hai-Lin CongInstitute of Biomedical Materials and Engineering, College of Chemistry and Chemical Engineering, Qingdao University, Qingdao, China;Laboratory for New Fiber Materials and Modern Textile, Growing Base for State Key Laboratory, College of Materials Science and Engineering, Qingdao University, Qingdao, ChinaCorrespondence[email protected]
,
Kai-Li YuanInstitute of Biomedical Materials and Engineering, College of Chemistry and Chemical Engineering, Qingdao University, Qingdao, China
&
Hui ZhangInstitute of Biomedical Materials and Engineering, College of Chemistry and Chemical Engineering, Qingdao University, Qingdao, China
Pages 134-138 | Received 05 Oct 2016, Accepted 07 Mar 2017, Published online: 02 Nov 2017
 
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ABSTRACT

“Selective etching based on structural differences” strategy to produce hollow nanosilica (sSiO2@mSiO2), which is different from the traditional composition of the core by using structural differences rather than the silica core or mesoporous silica Shell structure to create hollow interior. We synthesized highly dispersed hollow mesoporous silica spheres with unetched sSiO2 inside, which showed high loading capacity of the anticancer drug (doxorubicin).

5.  Funding

This work is financially supported by the National Natural Science Foundation of China (21375069, 21574072, 21675091, 21404065), the Natural Science Foundation for Distinguished Young Scientists of Shandong Province (JQ201403), the Taishan Young Scholar Program of Shandong Province (tsqn20161027), the Key Research and Development Project of Shandong Province (2016GGX102028, 2016GGX102039), the Project of Shandong Province Higher Educational Science and Technology Program (J15LC20), the Scientific Research Foundation for the Returned Overseas Chinese Scholars of State Education Ministry (20111568), the People's Livelihood Science and Technology Project of Qingdao (166257nsh), and the Postdoctoral Scientific Research Foundation of Qingdao.

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