ABSTRACT
Objective: To evaluate the serum survivin level in preeclampsia.
Methods: Eighty-eight pregnancies complicated with preeclampsia and 88 gestational-age (GA)-matched uncomplicated pregnancies were evaluated.
Results: Mean serum survivin was detected to be significantly decreased in the early- (EOPE) and late-onset (LOPE) preeclampsia subgroups than the GA-matched control-groups; and were comparable in EOPE- and LOPE-groups after correction for GA. Serum survivin had weak negative correlations with systolic and diastolic arterial blood pressure.
Conclusion: The serum survivin level was decreased in preeclamptic patients than the GA-matched controls. More comprehensive studies are needed to clarify the timing and extent of placental apoptosis in preeclampsia.
Acknowledgments
We would like to thank our beloved nurse Medine Eltutan from our pregnancy outpatient clinic in Istanbul Cerrahpasa University Hospital for her kind support and dedication during the patient recruitment.
Disclosure statement
No potential conflict of interest was reported by the author(s).
Supplementary material
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