Figures & data
TABLE 1 Effect of different skin pretreatment on the penetration data of trazodone hydrochloride delivered from matrix-type transdermal delivery system across mouse epidermis
TABLE 2 The penetration data of trazodone hydrochloride delivered from matrix-type transdermal delivery system containing essential oils through mouse epidermis
FIG. 1 Effect of essential oils on trazodone hydrochloride (TZN) percutaneous absorption after pretreatment with 10% essential oil/PG before application of control transdermal delivery system (TDS). Each data point represents mean ±SEM (n = 3).
![FIG. 1 Effect of essential oils on trazodone hydrochloride (TZN) percutaneous absorption after pretreatment with 10% essential oil/PG before application of control transdermal delivery system (TDS). Each data point represents mean ±SEM (n = 3).](/cms/asset/35d00d3a-7b69-466c-bcfe-387cefcbbf11/idrd_a_139489_uf0001_b.gif)
FIG. 2 Permeation profiles of TZN from TDS containing different concentration of eucalyptus oil without pretreatment across mouse epidermis. Each data point represents mean ±SEM (n = 3).
![FIG. 2 Permeation profiles of TZN from TDS containing different concentration of eucalyptus oil without pretreatment across mouse epidermis. Each data point represents mean ±SEM (n = 3).](/cms/asset/7ea8cd04-3e68-48fc-abbf-1e748c91aa5d/idrd_a_139489_uf0002_b.gif)
FIG. 3 Permeation profiles of TZN from TDS containing different concentration of fennel oil without pretreatment across mouse epidermis. Each data point represents mean ±SEM (n = 3).
![FIG. 3 Permeation profiles of TZN from TDS containing different concentration of fennel oil without pretreatment across mouse epidermis. Each data point represents mean ±SEM (n = 3).](/cms/asset/982b3a7a-fbdf-4d35-8559-fce36d1be193/idrd_a_139489_uf0003_b.gif)
FIG. 4 Permeation profiles of TZN from TDS containing different concentration of mentha oil without pretreatment across mouse epidermis. Each data point represents mean ±SEM (n = 3).
![FIG. 4 Permeation profiles of TZN from TDS containing different concentration of mentha oil without pretreatment across mouse epidermis. Each data point represents mean ±SEM (n = 3).](/cms/asset/1aea7469-9aa2-4165-aca4-b8700055b58a/idrd_a_139489_uf0004_b.gif)