FIG. 1 Cumulative release (in μg) of calcitonin (CT) from PLA in situ implants in different co-solvent combinations.
FIG. 2 Percent CT remaining in the PLA in situ implants at 1, 7, 14, 21, and 28 days.
FIG. 3 Storage stability of CT formulations over a 4-month period at (I) 4°, (II) 20°, and (III) 37°C.
FIG. 4 DSC thermograms of (A) BB only, (B) 80:20, (C) 60:40, (D) 50:50, and (E) 20:80 (BB:BA combinations) containing (F) CT and (G) PLA polymer.
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