Figures & data
Table 1. Composition, entrapment efficiency, vesicle diameter and ex vivo permeation parameters of TIZ-loaded nanotransfersomes.
Figure 1. In vitro release profiles of TIZ from drug solution and transfersomal formulae: (A) F1–F6 and (B) F7–F12.
![Figure 1. In vitro release profiles of TIZ from drug solution and transfersomal formulae: (A) F1–F6 and (B) F7–F12.](/cms/asset/8c4e5bdc-e5a9-49db-8e58-8a9b33dad7c2/idrd_a_1245369_f0001_c.jpg)
Figure 3. Morphology of rabbit rectal mucosa: (A) control, (B) 8 h after administration of FG and (C) 8 h after administration of TG.
![Figure 3. Morphology of rabbit rectal mucosa: (A) control, (B) 8 h after administration of FG and (C) 8 h after administration of TG.](/cms/asset/bc333785-8caa-433b-b587-7e868552b367/idrd_a_1245369_f0003_c.jpg)
Figure 4. Mean TIZ concentrations in rabbit plasma following administration of oral solution, rectal TIZ in situ gel (FG) and rectal transfersomal in situ gel (TG).
![Figure 4. Mean TIZ concentrations in rabbit plasma following administration of oral solution, rectal TIZ in situ gel (FG) and rectal transfersomal in situ gel (TG).](/cms/asset/38b8dd95-d9a4-4869-b71a-8c64d1abd2d0/idrd_a_1245369_f0004_c.jpg)