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Original

Hemoglobin-Vesicles as a Transfusion Alternative

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Pages 581-588 | Published online: 11 Jul 2009

Figures & data

Figure 1 Highly purified and concentrated human-derived Hb solution is encapsulated in phospholipid vesicles (liposomes). One particle contains about 30,000 Hb molecules. The outer surface of one HbV is modified with about 1,500 polymer chains of PEG that ensure the dispersion stability of HbV during storage and during circulation in the blood stream. The transmission electron micrograph (TEM) clearly depicts the well-regulated particle size and high Hb content within the vesicles.

Figure 1 Highly purified and concentrated human-derived Hb solution is encapsulated in phospholipid vesicles (liposomes). One particle contains about 30,000 Hb molecules. The outer surface of one HbV is modified with about 1,500 polymer chains of PEG that ensure the dispersion stability of HbV during storage and during circulation in the blood stream. The transmission electron micrograph (TEM) clearly depicts the well-regulated particle size and high Hb content within the vesicles.

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