Microspheres of Collagen/β-TCP with an Open Network Fibrillar Structure Strengthened by Chitosan

Figures & data

Figure 1 Flow chart depicting the process for preparing the chitosan-coated collagen/β-TCP microspheres.

Figure 2 Removal of alginate from chitosan-coated collagen/β-TCP/alginate gel beads by PBS. The chitosan-coated collagen/b-TCP/alginate gel beads were immersed in PBS 37°C. The amount of the alginate releasing from the gel beads was measured according to the method described by Halle [[10]].

Figure 3 Optical micrograph of a chitosan-coated collagen/β-TCP microsphere. The black spots are due to the non transparent β-TCP particulates.

Figure 4 SEM micrograph of the chitosan-coated collagen/β-TCP microsphere: (a) surface (magnification: × 10000), and (b) inner section (magnification: × 10000). The microsphere contains 35% w collagen and 65% w β-TCP microsphere.

Figure 5 Optical micrographs of the microspheres on the glass slide: (left) microspheres with chitosan coating; (right) a microspheres without chitosan coating.

Halle, J.P., Landry, D., Fournier, A., Beaudry, M., Leblond, A. (1993). Method for the quantification of alginate in microcapsules. Cell Transplant. 2: 429–436.

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