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Original

Encapsulation of PEG-Urease/PEG-AlaDH Within Sheep Erythrocytes and Determination of the System's Activity in Lowering Blood Levels of Urea in Animal Models

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Pages 391-403 | Published online: 11 Jul 2009

Figures & data

Table 1. Properties of PEG enzyme derivatives

Table 2. Storage stabilities of PEG enzyme derivatives at 4°C

Table 3. Encapsulation of PEG enzymes in erythrocytes

Table 4. Hemogram analysis of erythrocytes encapsulated at various urease/AlaDH activity ratios

Figure 1 Variation of average (a) blood urea, (b) blood ammonia values during the day in the dose control group injected with PEG enzyme preparation.

Figure 1 Variation of average (a) blood urea, (b) blood ammonia values during the day in the dose control group injected with PEG enzyme preparation.

Table 5. Daily variations of the blood urea values in the control group

Figure 2 Daily variation of blood urea level in the PEG enzyme group.

Figure 2 Daily variation of blood urea level in the PEG enzyme group.

Figure 3 Daily variation of blood urea level in the erythrocyte group.

Figure 3 Daily variation of blood urea level in the erythrocyte group.

Figure 4 Precipitation test in agarose gel. 1/10 dilution of PEG-urease (left) and PEG-AlaDH (right) were applied into the central cavities; serum samples from 3 immunological groups and 3 control groups were applied to peripheric cavities.

Figure 4 Precipitation test in agarose gel. 1/10 dilution of PEG-urease (left) and PEG-AlaDH (right) were applied into the central cavities; serum samples from 3 immunological groups and 3 control groups were applied to peripheric cavities.

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