Human Telomerase Reverse Transcriptase Expression Correlates with Vascular Endothelial Growth Factor-Promoted Tumor Cell Proliferation in Prostate Cancer

Figures & data

TABLE 1 Difference of hTERT expression between PCa and BPH

	Expression of hTERT
Group	Cases	−	+	++	Positive rate of hTERT (%)	P
PCa	60	22	12	26	63.3	< 0.05
BPH	60	50	10	0	16.7

Note: compared with BPH, P < 0.05.

Figure 1 Expression of hTERT in PCa (SP, × 400) Staining intensity was detected in the cytoplasm of tumor cells.

Figure 2 Expression of hTERT in BPH (SP, × 400) Staining intensity was detected in the cytoplasm.

TABLE 2 Difference of VEGF expressions between PCa and BPH

		Expression of VEGF
Group	Cases	−	+	++	Positive rate of VEGF (%)	P
PCa	60	14	28	18	76.7	< 0.05
BPH	60	32	22	6	46.7

Note: compared with BPH, P < 0.05.

Figure 3 Expression of VEGF in PCa (SP, × 400) Staining intensity was detected in the cytoplasm of tumor cells.

Figure 4 Expression of VEGF in BPH (SP, × 400) Staining intensity was detected in the cytoplasm.

TABLE 3 Correlation between hTERT and VEGF in Pca

	Expression of hTERT
Expression of VEGF	−	+	++	Total (cases)
−	10	4	0	14
+	8	16	4	28
++	4	6	8	18
Total (cases)	22	26	12	60

Note: P < 0.05.

TABLE 4 Correlation between hTERT and VEGF in BPH

	Expression of hTERT
Expression of VEGF	−	+	++	Total (cases)
−	27	4	1	32
+	12	2	1	15
++	11	1	1	13
Total (cases)	50	7	3	60

Note: P > 0.05.