The Experimental Study of Absorbable Chitin Conduit for Bridging Peripheral Nerve Defect with Nerve Fasciculu in Rats

Figures & data

Figure 1 The sciatic nerve defect model.

Figure 2 Biological chitin conduit block diagram.

Figure 3 Histological examination methods and sites.

Figure 4 The conduit shape in general observation after 6 weeks.

Figure 5 Regenerated nerve fiber in conduit and vessel on the conduit 10x.

Figure 6 Nerve graft.

Figure 7 Single conduit.

Figure 8 Fasciculu + conduit.

Figure 9 HE staining.

Figure 10 S100 staining.

Table 1 The motor nerve conduction velocity of three groups

Unit: m/s	The 6th week	The 12th week
Nerve graft group	29.44 ± 3.44	35.94 ± 4.25
Single conduit	19.74 ± 2.89	26.76 ± 3.46
Fasciculu + conduit	22.94 ± 3.89	30.18 ± 3.78

Table 2 Re-myelinated nerve axons counting in three groups

	The 6th week	The 12th week
Nerve graft group	42.43 ± 4.67	40.78 ± 3.98
Single conduit	28.41 ± 2.78	30.45 ± 4.89
Fasciculu+conduit	33.27 ± 3.69	35.58 ± 5.73

Table 3 Cross section area of distal re-myelinated nerve axons

	The 6th week	The 12th week
Nerve graft group	28.39	31.28
Single conduit	22.46	27.59
Fasciculu + conduit	23.15	29.78