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Artificial Cells, Blood Substitutes, and Biotechnology Volume 36, 2008 - Issue 4
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Original

The Study of Improved Controlled Release of Vincristine Sulfate from Collagen-Chitosan Complex Film

Hongli Chen Institute of Biomedical Engineering, Chinese Academy of Medical Sciences & Peking Union Medical College, The Key Laboratory of Biomedical Material of Tianjin, Tianjin, People's Republic of China
,
Han Chen Institute of Biomedical Engineering, Chinese Academy of Medical Sciences & Peking Union Medical College, The Key Laboratory of Biomedical Material of Tianjin, Tianjin, People's Republic of China
,
Lingrong Liu Institute of Biomedical Engineering, Chinese Academy of Medical Sciences & Peking Union Medical College, The Key Laboratory of Biomedical Material of Tianjin, Tianjin, People's Republic of China
,
Ping Yuan Institute of Biomedical Engineering, Chinese Academy of Medical Sciences & Peking Union Medical College, The Key Laboratory of Biomedical Material of Tianjin, Tianjin, People's Republic of China
&
Qiqing Zhang Institute of Biomedical Engineering, Chinese Academy of Medical Sciences & Peking Union Medical College, The Key Laboratory of Biomedical Material of Tianjin, Tianjin, People's Republic of China
Pages 372-385 | Published online: 11 Jul 2009

Figures & data

Figure 1 SEM images of the microspheres and film. A1. Collagen: Chitosan 1:0; A2. A1 degradation 2W; B1. Collagen:Chitosan 9:1; B2. B1 degradation 2W; C1. Collagen: Chitosan 4:1; C2. C1 degradation 2W; D1. Collagen:Chitosan 3:2; D2. D1 degradation 2W; E. microspheres.

Figure 1 SEM images of the microspheres and film. A1. Collagen: Chitosan 1:0; A2. A1 degradation 2W; B1. Collagen:Chitosan 9:1; B2. B1 degradation 2W; C1. Collagen: Chitosan 4:1; C2. C1 degradation 2W; D1. Collagen:Chitosan 3:2; D2. D1 degradation 2W; E. microspheres.

Figure 2 Tensile strength and breaking elongating rate of the film.

Figure 2 Tensile strength and breaking elongating rate of the film.

Figure 3 The degradation curve of the film in vitro.

Figure 3 The degradation curve of the film in vitro.

Figure 4 Release curve of the films in vitro.

Figure 4 Release curve of the films in vitro.

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