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Original

PEG-conjugated Hemoglobin Combination with Cisplatin Enforced the Antiangiogeic Effect in a Cervical Tumor Xenograft Model

, , , , , & show all
Pages 487-497 | Published online: 11 Jul 2009

Figures & data

Figure 1.  Representative photographs of serial changes in pre-established tumor volume during each treatment in BALB/c nude mice mice.

Figure 1.  Representative photographs of serial changes in pre-established tumor volume during each treatment in BALB/c nude mice mice.

Figure 2.  Tumor hypoxia reflected by (A) images of immunocytochemical staining of Hypoxyprobe-1 in tumor tissue, (B) Pimonidazole binding scores, and (C) expression of HIF-1α. *P < 0.05, **P < 0.05.

Figure 2.  Tumor hypoxia reflected by (A) images of immunocytochemical staining of Hypoxyprobe-1 in tumor tissue, (B) Pimonidazole binding scores, and (C) expression of HIF-1α. *P < 0.05, **P < 0.05.

Figure 3.  VEGF mRNA levels in nude mice tumor tissues and VEGF protein concentrations in the blood serum of the nude mice were assessed by RT-PCR (A) and ELISA (B), respectively. Data shown are representative of three independent experiments. *P < 0.05.

Figure 3.  VEGF mRNA levels in nude mice tumor tissues and VEGF protein concentrations in the blood serum of the nude mice were assessed by RT-PCR (A) and ELISA (B), respectively. Data shown are representative of three independent experiments. *P < 0.05.

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