355
Views
2
CrossRef citations to date
0
Altmetric
Original

The effect of poly-l-lysine/alginate bead membrane characteristics on the absorption of heparin

, , , &
Pages 13-22 | Published online: 11 Jul 2009

Figures & data

Table 1. Parameters of beads and solutions used in the total volume ratio experiments

Figure 1.  Fitted curves comparing heparin absorption rates under conditions where ratio of bead to solution volume is kept constant.

Figure 1.  Fitted curves comparing heparin absorption rates under conditions where ratio of bead to solution volume is kept constant.

Table 2. Parameters of beads and solutions used in the surface area ratio experiments.

Figure 2.  Fitted curves comparing heparin absorption rates under conditions where the ratio of the total surface area of the beads to the volume of the solution is kept constant.

Figure 2.  Fitted curves comparing heparin absorption rates under conditions where the ratio of the total surface area of the beads to the volume of the solution is kept constant.

Figure 3.  Comparison of the adsorption of heparin by beads with varying concentrations of sodium alginate. The two curves are not easily distinguishable due to being superimposed.

Figure 3.  Comparison of the adsorption of heparin by beads with varying concentrations of sodium alginate. The two curves are not easily distinguishable due to being superimposed.

Figure 4.  Adsorption of heparin by beads with no membrane.

Figure 4.  Adsorption of heparin by beads with no membrane.

Figure 5.  Microscopic photograph of the 900 µm and 2 mm beads illustrating the different membrane thickness.

Figure 5.  Microscopic photograph of the 900 µm and 2 mm beads illustrating the different membrane thickness.

Table 3. Parameters used in the bead membrane volume ratio experiments.

Figure 6.  Comparison of heparin absorption rate under conditions where the ratio of the membrane volume of the beads remains constant.

Figure 6.  Comparison of heparin absorption rate under conditions where the ratio of the membrane volume of the beads remains constant.

Figure 7.  K-values for various membrane volumes of the beads.

Figure 7.  K-values for various membrane volumes of the beads.

Figure 8.  Data points fitted to Freundlich Isotherm using the volume of membrane of the beads.

Figure 8.  Data points fitted to Freundlich Isotherm using the volume of membrane of the beads.

Figure 9.  Microscopic photograph of 2 mm beads placed in poly-L-lysine solution for 20 minutes and 40 minutes, respectively.

Figure 9.  Microscopic photograph of 2 mm beads placed in poly-L-lysine solution for 20 minutes and 40 minutes, respectively.

Figure 10.  Microscopic photograph of 2 mm beads placed in poly-L-lysine solution for 20 minutes and 60 minutes, respectively.

Figure 10.  Microscopic photograph of 2 mm beads placed in poly-L-lysine solution for 20 minutes and 60 minutes, respectively.

Figure 11.  Rates of heparin removal using beads with varying poly-L-lysine content.

Figure 11.  Rates of heparin removal using beads with varying poly-L-lysine content.

Table 4. Rate coefficients for the beads with varying poly-L-lysine (PLL) content

Figure 12.  Comparison of the rate of heparin adsorption in fetal calf serum (FCS) and saline.

Figure 12.  Comparison of the rate of heparin adsorption in fetal calf serum (FCS) and saline.

Figure 13.  Comparison of the rate of heparin adsorption in blood, fetal calf serum and saline.

Figure 13.  Comparison of the rate of heparin adsorption in blood, fetal calf serum and saline.

Table 5. Rate coefficients for blood, FCS and saline

Figure 14.  Comparison of the rate of heparin using different pH solutions.

Figure 14.  Comparison of the rate of heparin using different pH solutions.

Table 6. Rate Coefficients for the first order adsorption model

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.