The Influence of Brain Injury or Peripheral Nerve Injury on Calcitonin Gene-Related Peptide Concentration Variation and Fractures Healing Process

Figures & data

Figure 1.  The X-ray to display the fracture healing conditions in 4 different groups in different time.

Figure 2.  The HE staining to display the bone callus condition in different groups at 2 weeks.

Table 1. The variation of CGRP concentration in blood plasma (pg/ml)

	Time of after injury(d)
Groups	0d	2d	7d	14d	28d
Group A	8.80±6.10	5.79±4.69	3.03±0.87	13.32±16.39	4.45±1.21
Group B	7.51±7.09	2.91±1.47	2.64±1.76	4.19±2.71	78.89±118.90
Group C	7.46±3.72	3.17±1.46	2.49±0.77	6.04±4.73	5.13±1.19
Group D	8.73±4.24	5.39±2.95	2.87±1.11	6.00±1.63	9.20±2.33

The variation column diagram of CGRP concentration in blood serum at different times after fracture of animals.

Table 2. The variation of CGRP concentration in spinal anterior motorneuron (pg/ml)

	Time of after injury(d)
Groups	7d	14d	28d
Group A	2396.19±819.78	2176.69±1006.92	1786.38±644.88
Group B	2188.42±398.05	1991.04±1642.31	1968.87±603.50
Group C	2148.45304.09	1786.08±820.96	1824.16±1628.37
Group D	2305.34±587.43	2210.58±529.81	2333.71±1027.86

The variation column diagram of CGRP concentration in spinal anterior motor neuron at different times after fracture of animals.

Table 3. The variation of CGRP concentration in dorsal root ganglion (pg/ml)

	Time of after injury(d)
Groups	7d	14d	28d
Group A	37200.73±20315.64	12143.67±3129.19	8908.30±3999.77
Group B	46486.54±15052.26	5739.09±2679.03	29236.40±6185.04
Group C	11207.70±1604.74	27621.74±13120.23	80162.31±15711.83
Group D	22378.22±9122.83	14667.37±8658.43	28356.07±12610.88

The variation column diagram of CGRP concentration in in dorsal root ganglion at different times after fracture of animals.