561
Views
0
CrossRef citations to date
0
Altmetric
Research Articles

MicroRNA-124a regulates the differentiation of bone marrow mesenchymal stem cells into neurons

, , , , , , , & show all
Pages 154-159 | Received 23 Oct 2023, Accepted 23 Dec 2023, Published online: 16 Jan 2024

Figures & data

Figure 1. Appraisal of BMSCs and analyzed using flow cytometry. Flow cytometry for sorting of BMSCs.

Figure 1. Appraisal of BMSCs and analyzed using flow cytometry. Flow cytometry for sorting of BMSCs.

Figure 2. MicroRNA-124a mRNA expression of BMSCs. (A) β-Thiol ethanol reduced microRNA-124a expression of BMSCs. (B) Baicalin reduced microRNA-124a expression of BMSCs. *p < 0.05 compared with β-thiol ethanol at 0 h group or baicalin at 0 h group.

Figure 2. MicroRNA-124a mRNA expression of BMSCs. (A) β-Thiol ethanol reduced microRNA-124a expression of BMSCs. (B) Baicalin reduced microRNA-124a expression of BMSCs. *p < 0.05 compared with β-thiol ethanol at 0 h group or baicalin at 0 h group.

Figure 3. β-thiol ethanol or baicalin controlled apoptosis of BMSCs. (A) β-Thiol ethanol reduced apoptosis of BMSCs. (B) Baicalin reduced apoptosis of BMSCs. *p < 0.05 compared with β-thiol ethanol at 0 h group or baicalin at 0 h group.

Figure 3. β-thiol ethanol or baicalin controlled apoptosis of BMSCs. (A) β-Thiol ethanol reduced apoptosis of BMSCs. (B) Baicalin reduced apoptosis of BMSCs. *p < 0.05 compared with β-thiol ethanol at 0 h group or baicalin at 0 h group.

Figure 4. MicroRNA-124a inhibitor reduced microRNA-124a expression in BMSCs. The RT-PCR results of microRNA-124a expression. *p < 0.05 compared with β-thiol ethanol at 0 h group or baicalin at 0 h group.

Figure 4. MicroRNA-124a inhibitor reduced microRNA-124a expression in BMSCs. The RT-PCR results of microRNA-124a expression. *p < 0.05 compared with β-thiol ethanol at 0 h group or baicalin at 0 h group.

Figure 5. MicroRNA-124a is one target for the effects of β-thiol ethanol or baicalin on cell growth of BMSCs. The MTT results of BMSCs with different treatment. *p < 0.05 compared with inhibit NC.

Figure 5. MicroRNA-124a is one target for the effects of β-thiol ethanol or baicalin on cell growth of BMSCs. The MTT results of BMSCs with different treatment. *p < 0.05 compared with inhibit NC.

Figure 6. MicroRNA-124a Is one target for the effects of β-thiol ethanol or baicalin on apoptosis of BMSCs. (A) Apoptosis rate of BMSCs. (B) Apoptosis assay using flow cytometry. *p < 0.05 compared with inhibit NC.

Figure 6. MicroRNA-124a Is one target for the effects of β-thiol ethanol or baicalin on apoptosis of BMSCs. (A) Apoptosis rate of BMSCs. (B) Apoptosis assay using flow cytometry. *p < 0.05 compared with inhibit NC.